Is natural progesterone safe to use long-term?

Yes, many women use progesterone continuously to manage symptoms of oestrogen dominance, peri-menopause, menopause, and other hormonal imbalances — with positive long-term outcomes.

Progesterone is one of the oldest hormones on earth —it is essential to vertebrate life. Its safety profile is well established through both long-term use and extensive research.

It is important to use the correct dose for your individual needs, using too little could aggravate estrogen dominance symptoms.

For a comprehensive list of research references, visit progesterone research papers.